Age Estimation in Living Egyptians Using Signal Joint T-cell Receptor Excision Circle Rearrangement
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[1] Cairo University
Cairo University
Egipto
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- Localización: Journal of forensic sciences, ISSN-e 1556-4029, ISSN 0022-1198, Vol. 61, Nº. 4, 2016, págs. 1107-1111
- Idioma: inglés
- Texto completo no disponible (Saber más ...)
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Resumen
Age estimation is one of the challenges in forensic sciences. There are many techniques to estimate the age. Molecular biology approach is one of these techniques. Signal joint T-cell receptor excision circles gene (sjTRECs), is one of this approach. We aimed to use sjTRECs as a suitable marker for age estimation among Egyptian population. TaqMan qPCR approach was used to quantify sjTREC levels in blood samples obtained from 153 healthy Egyptian individuals ranging from a few weeks to 70 years. Our results showed a significant negative correlation between sjTREC levels and age with p ≤ 0.05. Moreover, the individual’s age can be determined through this formula Age = -30.671+ (-5.998Y)(Y is dCtTBP - sjTREC) with standard error+ -7.35 years. Within the forensic context, sjTREC’ levels can beused to estimate the Egyptian individual’s age accurately.
