Upper lip malignant neoplasms: a study of 59 cases

Kuauhyama Luna-Ortiz ^[1] ; Agustín Güemes-Meza ^[3] ; Verónica Villavicencio-Valencia ^[3] ; Adalberto Mosqueda-Taylor ^[2]
1. [1] Universidad Nacional Autónoma de México
  
  Universidad Nacional Autónoma de México
  
  México
2. [2] Universidad Autónoma Metropolitana
  
  Universidad Autónoma Metropolitana
  
  México
3. [3] Department of Head and Neck Surgery, Instituto Nacional de Cancerología, México
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Localización: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, ISSN-e 1698-6946, Vol. 17, Nº. 3 (Mayo), 2012
Idioma: inglés
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Resumen
- Objectives: To present the demographic data, clinico-pathologic features and therapeutic outcome of a series of upper lip malignancies.
  
  Study Design: Retrospective study at a single Cancer Institution in Mexico City during a 14-year period.
  
  Results: There were 59 cases, (30 males and 29 females); age range: 14 to 106 years (mean: 73 yr.). Antecedents of ultraviolet light and tobacco exposure were found in 20 (33.9%) and 16 cases (27%) respectively. There were 35 squamous cell carcinomas (59.3%), 19 basal cell carcinomas (32.2%) and one case each (1.7%) of adenocarcinoma NOS, adenoid cystic carcinoma, angiosarcoma, Merkel cell carcinoma and melanoma. There were 14 cases in stage I (23.7%), 14 in stage II (23.7%), 3 in stage III (5.1%) 14 in stage IV (23.7%) and 14 were not classified (23.7%). There were no significant differences with respect to the overall survival curve and the disease-free survival curve among surgical treatment and radiotherapy. In addition, there was not statistically significant difference in the overall survival and disease-free survival among squamous cell carcinoma and basal cell carcinoma cases with respect to the type of treatment.
  
  Conclusions: Upper lip malignant neoplasms are infrequent lesions. The present series describes the main clinico-pathological features in a hospital-based population in Mexico city and demonstrates some differences with respect to those found in the lower lip.