Resumen de Breaking the HAC Barrier: Histone H3K9 acetyl/methyl balance regulates CENP-A assembly

Jun-ichirou Ohzeki, Jan H Bergmann, Natalay Kouprina, Vladimir N Noskov, Megumi Nakano, Hiroshi Kimura, William C. Earnshaw, Vladimir Larionov, Hiroshi Masumoto

• Establishment of Human Artificial Chromosomes (HACs) depends on an interplay of H3 lysine 9 modifications at centromeres, providing insights into the pathways that control incorporation of the kinetochore-specificing histone H3 variant CENP-A.