Three-dimensional structure of basal body triplet revealed by electron cryo-tomography

• Sam Li ^[1] ; Jose-Jesus Fernandez ^[3] ; Wallace F Marshall ^[2] ; David A Agard ^[1]
  1. [1] Howard Hughes Medical Institute

     Howard Hughes Medical Institute

     Estados Unidos

     
  2. [2] University of California, San Francisco

     University of California, San Francisco

     Estados Unidos

     
  3. [3] Centro Nacional de Biotecnologia—CSIC, Campus Universidad Autonoma, Madrid, Spain

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• Localización: EMBO journal: European Molecular Biology Organization, ISSN 0261-4189, Vol. 31, Nº. 3, 2011, págs. 552-562
• Idioma: inglés
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• Resumen

  • The basal body, derived from the centriole, is a microtubule-organizing organelle that nucleates the cilium in non-dividing cells. Cryo-electron tomography reveals the overall structure of this organelle, and provides insights its biogenesis and function.