Dpb11 coordinates Mec1 kinase activation with cell cycle-regulated Rad9 recruitment

• Boris Pfander ^[1] ; John F X Diffley ^[1]
  1. [1] London Research Institute

     London Research Institute

     Reino Unido

     
• Localización: EMBO journal: European Molecular Biology Organization, ISSN 0261-4189, Vol. 30, Nº. 24, 2011, págs. 4897-4907
• Idioma: inglés
• Enlaces
  • Texto completo
• Resumen

  • Cyclin-dependent kinase phosphorylation of the replication checkpoint mediator Rad9 controls its association with Dpb11, a key activator of the yeast ATR homologue Mec1, thus conferring cell-cycle dependence to checkpoint signalling.