Arrangement of electron transport chain components in bovine mitochondrial supercomplex I1III2IV1

• Thorsten Althoff ^[1] ; Deryck J Mills ^[1] ; Jean-Luc Popot ^[2] ; Werner Kühlbrandt ^[1]
  1. [1] Max Planck Institute of Biophysics

     Max Planck Institute of Biophysics

     Frankfurt, Alemania

     
  2. [2] Institut de Biologie Physico-Chimique UMR 7099, CNRS et Université Paris, Paris, France
• Localización: EMBO journal: European Molecular Biology Organization, ISSN 0261-4189, Vol. 30, Nº. 22, 2011, págs. 4652-4664
• Idioma: inglés
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• Resumen

  • The respiratory chain complexes of the mitochondrial inner membrane are organized as three higher-order multi-enzyme complexes. This study puts forward the first cryo-EM map for one of these supercomplexes and provides insight into possible pathways for efficient electron transfer.