Resumen de Multiple modalities converge on a common gate to control K2P channel function

Sviatoslav N Bagriantsev, Rémi Peyronnet, Kimberly A Clark, Eric Honoré, Daniel L Minor

• K2P potassium channels play important roles in the regulation of neuronal excitability. K2P channels are gated chemical, thermal, and mechanical stimuli, and the present study identifies and characterizes a common molecular gate that responds to all different stimuli, both activating and inhibitory ones.