The SWI/SNF complex acts to constrain distribution of the centromeric histone variant Cse4

• Triantaffyllos Gkikopoulos ^[1] ; Vijender Singh ^[1] ; Kyle Tsui ^[2] ; Salma Awad ^[1] ; Matthew J Renshaw ^[1] ; Pieta Scholfield ^[1] ; Geoffrey J Barton ^[1] ; Corey Nislow ^[2] ; Tomoyuki U Tanaka ^[1] ; Tom Owen-Hughes ^[1]
  1. [1] University of Dundee

     University of Dundee

     Reino Unido

     
  2. [2] University of Toronto

     University of Toronto

     Canadá

     
• Localización: EMBO journal: European Molecular Biology Organization, ISSN 0261-4189, Vol. 30, Nº. 10, 2011, págs. 1919-1927
• Idioma: inglés
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• Resumen

  • The SWI/SNF complex has an important role in regulating chromatin structure during transcriptional activation and DNA repair. Here, the SWI/SNF complex is also involved in the organisation of centromeric chromatin and prevention of the ectopic deposition of centromeric histone variants.