Membrane curvature during peroxisome fission requires Pex11

• Łukasz Opaliński ^[1] ; Jan A K W Kiel ^[1] ; Chris Williams ^[2] ; Marten Veenhuis ^[1] ; Ida J van der Klei ^[1]
  1. [1] Molecular Cell Biology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Kluyver Centre for Genomics of Industrial Fermentation, Haren, The Netherlands
  2. [2] EMBL Hamburg Outstation, c/o DESY, Hamburg, Germany
• Localización: EMBO journal: European Molecular Biology Organization, ISSN 0261-4189, Vol. 30, Nº. 1, 2010, págs. 5-16
• Idioma: inglés
• Enlaces
  • Texto completo
• Resumen

  • Pex11p is required for peroxisome proliferation. This study demonstrates that the N-terminus of Pex11p forms an amphipathic helix that generates membrane curvature required for peroxisome fission.