Zic2 regulates the expression of Sert to modulate eye-specific refinement at the visual targets

• Cristina Garcia Frigola ; Eloísa Herrera ^[1]
  1. [1] Consejo Superior de Investigaciones Científicas

     Consejo Superior de Investigaciones Científicas

     Madrid, España

     
• Localización: EMBO journal: European Molecular Biology Organization, ISSN 0261-4189, Vol. 29, Nº. 18, 2010, págs. 3170-3183
• Idioma: inglés
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• Resumen

  • This neurodevelopmental paper reports on the transcription factor Zic2 as critical regulator of visual target refinement. Establishing that Zic2 acts through the serotonin transporter SERT provides insight into a critical element of visual circuitry.