Feverish Quest for Ebola Immunotherapy: Straight or Cocktail?

• Autores: Erica Ollmann Saphire, M.Javad Aman
• Localización: Trends in microbiology, ISSN 0966-842X, Vol. 24, Nº. 9, 2016, págs. 684-686
• Idioma: inglés
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• Resumen

  • The ebolavirus immunotherapeutics field has replaced previous perceptions of antibody inadequacy with a new abundance of monoclonals exhibiting post exposure efficacy. Now the questions are: what epitopes to target, what immunological mechanisms to seek, whether species-specific or broadly reactive antibodies are best, and whether a cocktail or monotherapy should be used