Current methods of sedation in dental patients: a systematic review of the literature

• Jose-Ramón Corcuera-Flores ^[1] ; Javier Silvestre-Rangil ^[2] ; Antonio Cutando-Soriano ^[3] ; Julián López-Jiménez ^[4]
  1. [1] Universidad de Sevilla

     Universidad de Sevilla

     Sevilla, España

     
  2. [2] Universitat de València

     Universitat de València

     Valencia, España

     
  3. [3] Universidad de Granada

     Universidad de Granada

     Granada, España

     
  4. [4] PhD, MD, DDS. “Nen Deu” Private Practice Hospital, Barcelona, Spain

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• Localización: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, ISSN-e 1698-6946, Vol. 21, Nº. 5 (Septiembre), 2016
• Idioma: inglés
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• Resumen

  • The main objective of this systematic literature review is to identify the safest and most effective sedative drugs so as to ensure successful sedation with as few complications as possible.

    A total of 21 studies were selected due to their rigorous study design and conduciveness to further, more exhaustive analysis. The selected studies included a total of 1,0003 patients classified as ASA I or II. Midazolam was the drug most frequently used for successful sedation in dental surgical procedures. Ketamine also proved very useful when administered intranasally, although some side effects were observed when delivered via other routes of administration. Both propofol and nitrous oxide (N2O) are also effective sedative drugs.

    Midazolam is the drug most commonly used to induce moderate sedation in dental surgical procedures, and it is also very safe. Other sedative drugs like ketamine, dexmedetomidine and propofol have also been proven safe and effective; however, further comparative clinical studies are needed to better demonstrate which of these are the safest and most effective.