Autism Spectrum Disorders and Ehlers-Danlos Syndrome Hypermobility-Type: Similarities in clinical presentation

• Autores: Carolina Baeza Velasco, Claude Hamonet, Amaria Baghdadli, Régine Brissot
• Localización: Cuadernos de medicina psicosomática y psiquiatria de enlace, ISSN 1695-4238, Nº. 118, 2016, págs. 49-58
• Idioma: inglés
• Títulos paralelos:
  • Trastornos del Espectro Autista y Síndrome de Ehlers-Danlos Hipermóvil: Similitudes en la presentación clínica
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• Resumen

  • Abstract Autism Spectrum Disorder (ASD) is an etiologically and clinically heterogeneous group of neurodevelopmental conditions, characterized by impairments in communication, social interaction and restricted repetitive and stereotyped behaviors. Ehlers-Danlos Syndrome hypermobility-type (EDS-HT; also known as Joint Hypermobility Syndrome), is the most common hereditary disorder of the connective tissue. It is characterized by joint hypermobility and a wide range of articular and non-articular manifestations, including disturbances in different systems due to the widespread distribution of collagen in the body. The clinical presentations of ASD and EDS-HT share several similar features, and although literature that relates these two conditions is scarce, it suggests that a connective tissue disorder may contribute to autistic symptomatology. The present work reviews the similarities in the clinical presentation of both conditions. In addition, the case of a 12-year-old boy diagnosed with ASD in which autistic manifestations overlap and/or might be explained by the presence of EDS-HT is presented as illustration