Detecting inconsistency in biological molecular databases using ontologies

• Qingfeng Chen ^[1] ; Yi-Ping Phoebe Chen ^[1] ; Chengqi Zhang ^[2]
  1. [1] Deakin University

     Deakin University

     Australia

     
  2. [2] University of Technology

     University of Technology

     Rusia

     
• Localización: Data mining and knowledge discovery, ISSN 1384-5810, Vol. 15, Nº 2, 2007, págs. 275-296
• Idioma: inglés
• Texto completo no disponible (Saber más ...)
• Resumen

  • The rapid growth of life science databases demands the fusion of knowledge from heterogeneous databases to answer complex biological questions. The discrepancies in nomenclature, various schemas and incompatible formats of biological databases, however, result in a significant lack of interoperability among databases. Therefore, data preparation is a key prerequisite for biological database mining. Integrating diverse biological molecular databases is an essential action to cope with the heterogeneity of biological databases and guarantee efficient data mining. However, the inconsistency in biological databases is a key issue for data integration. This paper proposes a framework to detect the inconsistency in biological databases using ontologies. A numeric estimate is provided to measure the inconsistency and identify those biological databases that are appropriate for further mining applications. This aids in enhancing the quality of databases and guaranteeing accurate and efficient mining of biological databases.