Combination Pill for Cardiovascular Disease—Reply

• Autores: Simon Thom, Anthony Rodgers
• Localización: JAMA: the journal of the American Medical Association, ISSN 0098-7484, Vol. 311, Nº. 1, 2014, págs. 93-93
• Idioma: inglés
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• Resumen

  • Drs Tsujimoto and Yamamoto-Honda note that improvements in adherence are of benefit in terms of increasing uptake of proven antiplatelet therapy, but question the importance of the improvements in mean LDL-C level and SBP. In contrast to their suggestion, in high-risk cardiovascular patients there is clear evidence of benefits of blood pressure lowering in patients without hypertension and of more vs less blood pressure lowering1- 3; similarly, there are benefits of LDL-C level lowering in patients without hyperlipidemia and of more vs less LDL-C level lowering.4,5