Epiphany root canal sealer prepared with resinous solvent is irritating to rat subcutaneous tissues

• Autores: Élcio Daleffe, José-Estevam Vieira-Ozorio, Manoel-Damião Sousa-Neto, Danyel Elias da Cruz Perez
• Localización: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, ISSN-e 1698-6946, Vol. 17, Nº. 4 (Julio), 2012
• Idioma: inglés
• Enlaces
  • Texto completo
• Resumen

  • Objective: This study assessed the biocompatibility of the Epiphany endodontic sealer prepared with resinous solvent of Epiphany system (Thinning resin) in rat subcutaneous tissues.

    Study D esign: Polyethylene tubes were filled with the sealer and 4 groups were established: GI, Epiphany prepared with 1 drop of resinous solvent (RS); GII, Epiphany prepared with 1 drop of RS and photoactivated; GIII, Epiphany associated with self-etch primer and prepared with 1 drop of RS; GIV, Epiphany associated with self-etch primer, prepared with 1 drop of RS and photoactivated. The filled tubes were implanted into 4 different regions of the dorsum of 20 adult male rats.

    Results: After 7, 14 and 21 days, all groups presented a moderate to severe chronic inflammation, necrosis and foreign-body giant cells. At 42 days, although the intensity of chronic inflammatory reaction decreased, the other features still were observed.

    Conclusion: The Epiphany sealer prepared with the RS was irritating to rat subcutaneous tissues.