Cancer: An essential passenger with p53.

• Autores: James E. Bradner
• Localización: Nature: International weekly journal of science, ISSN 0028-0836, Vol. 520, Nº 7549, 2015, págs. 626-626
• Idioma: inglés
• Texto completo no disponible (Saber más ...)
• Resumen

  • Deletion of the TP53 gene, an event seen in colorectal cancers, often occurs with co-deletion of a gene that encodes an enzyme subunit governing gene transcription. This creates a vulnerability ripe for therapeutic development. See Letter p.697