Cardiorespiratory Fitness, Sedentary Time, and Cardiovascular Risk Factor Clustering.

• Autores: Javaid Nauman, Dorthe Stensvold, Ulrik Wisløff, Jeff S. Coombes
• Localización: Medicine & Science in Sports & exercise: Official Journal of the American College of Sports Medicine, ISSN 0195-9131, Vol. 48, Nº. 4, 2016, págs. 625-632
• Idioma: inglés
• Texto completo no disponible (Saber más ...)
• Resumen

  • AB Purpose: Prolonged sedentary time (ST) is associated with cardiovascular risk factors (CV-RF) independent of physical activity (PA). Whether a high level of cardiorespiratory fitness (CRF) can modify the deleterious health consequences related to high ST is not known. Methods: We performed a cross-sectional study of 12,274 men and 14,209 women (>=20 yr) without known cardiovascular disease. Self-reported ST measurements during a regular day were divided into three sex-specific equally sized groups (<=4, 5 to <7, and >=7 h[middle dot]d-1). CRF was estimated (eCRF) using a previously validated nonexercise model. Using logistic regression analyses, adjusted odds ratios (OR) and 95% confidence intervals (CI) were estimated for the association of ST with CV-RF clustering and for the potential modifying effect of eCRF. Results: Each hour increase in ST was associated with 5% and 4% greater likelihood of having CV-RF clustering independent of PA in men and women, respectively. Among the participants with higher levels of eCRF, the adjusted OR values associated with >=7 h[middle dot]d-1 of ST were 0.92 (0.56-1.51) for men and 1.16 (0.49-2.74) for women, compared with men and women with low ST (<=4 h[middle dot]d-1) and high eCRF levels. In combined analyses of eCRF, PA, and ST, compared with the reference group of participants meeting the recommendations, <=4 h[middle dot]d-1 of ST and high eCRF, the OR values were 0.63 (0.27-1.44) and 0.65 (0.14-3.07) in fit men and women with >=7 h[middle dot]d-1 of ST, which did not meet the recommendations. Men and women meeting the PA recommendations, but were unfit, had significantly increased odds of having CV-RF clustering across levels of ST. Conclusion: High levels of eCRF abolished the increased odds of having CV-RF clustering associated with high ST, even among those individuals who did not meet the current PA recommendations.