Combined Training Reduces Subclinical Inflammation in Obese Middle-Age Men.

• Autores: Diego T. Brunelli, Claudia Regina Cavaglieri, Mara Patrícia Traina Chacon-Mikahil, Cleiton Augusto Libardi, Valeria Bonganha, Maria Luisa Bellotto, Ivan Luiz P. Bonfante, Wendell Arthur Lopes, Arthur F. Gaspari
• Localización: Medicine & Science in Sports & exercise: Official Journal of the American College of Sports Medicine, ISSN 0195-9131, Vol. 47, Nº. 10, 2015, págs. 2207-2215
• Idioma: inglés
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• Dialnet Métricas: 4 Citas
• Resumen

  • AB Purpose: We investigated the effects of 24 wk of combined training on proinflammatory and anti-inflammatory markers associated with obesity in obese middle-age men. Methods: Thirty obese men (48.73 +/- 1.04 yr; body mass index, 31.00 +/- 0.29 kg[middle dot]m-2) underwent 24 wk of combined training [CT (N = 17), aerobic (50%-85% of V[spacing dot above]O2peak) and resistance (6-10 maximum repetition [RM]) training)] three times per week, 60 min per session, or a control group (N = 13). Anthropometric measures, maximal strength for leg press and bench press, peak oxygen uptake (V[spacing dot above]O2peak) and serum concentrations of C-reactive protein (CRP), tumor necrosis factor [alpha] (TNF-[alpha]), interleukin-6 (IL-6), IL-10, IL-15, resistin, leptin, and adiponectin were determined before (M1) and after 8 (M2), 16 (M3), and 24 (M4) wk of the experimental design. Results: Significant increases were observed in the maximal strength for bench press and leg press, V[spacing dot above]O2peak, and serum concentrations of adiponectin and IL-15 for CT. Concomitantly, significant decreases were observed in percentage body fat and serum concentrations of CRP, resistin, and leptin for CT after the experimental period. Conclusion: Twenty-four weeks of moderate- to high-intensity CT reduced markers of subclinical inflammation associated with obesity and improved insulin resistance and functional capabilities of obese middle-age men, regardless of dietary intervention and weight loss. (