Hepatitis C Screening in the General Population

• Autores: Clara Corona Lau, Linda Elsa Muñoz Espinosa, Enrique Wolpert Barraza, Luz Mª. Aguilar Valenzuela, Margarita Dehesa, María Concepción Gutiérrez Ruiz, David Kershenobich Stalnikowitz
• Localización: Revista de investigación clínica, ISSN 0034-8376, ISSN-e 2564-8896, Vol. 67, Nº. 2, 2015, págs. 104-108
• Idioma: inglés
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• Resumen

  • Background: A significant number of patients infected with hepatitis C virus remain unaware of their infection, as this is a silent disease for many years. Patients are frequently detected at advance stages of the disease. Objective: To identify the prevalence and viremic stage of hepatitis C among a general population cohort. Methods: Anti-hepatitis C virus detection and viral RNA were offered without cost to individuals who voluntarily considered it relevant to be examined, as part of the World Hepatitis Day annually from 2007-2014. Results: A total of 32,945 individuals were analyzed; 57% were female and 43% male. Of them, 75.7% were between 21-50 years old. In 59%, the sample was obtained at their work place and in 41% at the facilities of 12 private laboratories. Anti-hepatitis C virus was positive in 194 patients (0.58%), of which 129 (66%) were confirmed positive by polymerase chain reaction. The overall prevalence of viremic cases in the sample was 0.39%. Conclusions: Adequate estimation of the prevalence of anti-hepatitis C virus and viremic population, not only among high-risk groups but also in the general population, is central to the allocation of resources in an effort to reduce the consequences of the disease. (REV INVES CLIN. 2015;67:104-8) Corresponding author: David Kershenobich, kesdhipa@yahoo.com