Clinical Predictors of Ventilatory Threshold Achievement in Patients with Claudication.

• Autores: Breno Q. Farah, Andrew W Gardner, Raphael M. Ritti-Dias, Gabriel G. Cucato, Annelise Lins Meneses
• Localización: Medicine & Science in Sports & exercise: Official Journal of the American College of Sports Medicine, ISSN 0195-9131, Vol. 47, Nº. 3, 2015, págs. 493-497
• Idioma: inglés
• Texto completo no disponible (Saber más ...)
• Resumen

  • AB Purpose: Ventilatory threshold (VT) is considered a clinically important marker of cardiovascular function in several populations, including patients with claudication, because it is related to walking capacity and hemodynamics. The purpose of this study was to identify clinical predictors for VT achievement in patients with intermittent claudication. Methods: One hundred and seventy-seven (n = 177) patients with intermittent claudication performed a progressive graded cardiopulmonary treadmill test until maximal claudication pain. Oxygen uptake (V[spacing dot above]O2) was continuously measured during the test, and afterwards, VT was visually detected. Clinical characteristics, demographic data, comorbid conditions, and cardiovascular risk factors were obtained. Patients who achieved and did not achieve VT were compared, as well as the workload that VT occurred in the former group. Results: VT was achieved in 134 patients (76%), and the mean V[spacing dot above]O2 at VT for these patients was 10.8 +/- 2.4 mL[middle dot]kg-1[middle dot]min-1. Patients who did not achieve VT presented lower ankle brachial index (ABI), claudication onset time, peak walking time, and V[spacing dot above]O2peak, and the proportion of women was higher compared with patients who achieved VT (P < 0.05). Multiple linear regression analysis identified that sex (b = 0.25, P = 0.002), body mass index (b = -0.18, P = 0.025), peak walking time (b = 0.17, P = 0.044), and ABI (b = 0.23, P = 0.006) were predictors of V[spacing dot above]O2 at VT. Conclusions: Forty-three patients (24%) with intermittent claudication did not achieve VT, and these patients were mostly women and those with greater severity of disease. Moreover, in those who reached VT, the predictors of poor VT were female sex, high body mass index, low peak walking time, and low ABI.