Human Granulocytic Anaplasmosis

• Autores: Johan S. Bakken, J. Stephen Dumler
• Localización: Infectious disease clinics of North America, ISSN 0891-5520, Vol. 29, Nº. 2, 2015 (Ejemplar dedicado a: Lyme Disease and Other Infections Transmitted by Ixodes scapularis), págs. 341-355
• Idioma: inglés
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• Resumen

  • Human granulocytic anaplasmosis, a deer tick–transmitted rickettsial infection caused by Anaplasma phagocytophilum, is a common cause of undifferentiated fever in the northeast and upper Midwest United States. Patients are often initially diagnosed with a mild viral infection, and illness readily resolves in most cases. However, as many as 3% develop life-threatening complications and nearly 1% die from the infection. Although coinfections with Borrelia burgdorferi and Babesia microti occur, there is little evidence to suggest synergism of disease or a role for A phagocytophilum in chronic illness. No vaccine is available.