Erythema Migrans

• Autores: Robert B. Nadelman
• Localización: Infectious disease clinics of North America, ISSN 0891-5520, Vol. 29, Nº. 2, 2015 (Ejemplar dedicado a: Lyme Disease and Other Infections Transmitted by Ixodes scapularis), págs. 211-239
• Idioma: inglés
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• Resumen

  • Erythema migrans (EM) is the most common objective manifestation of Borrelia burgdorferi infection. Systemic symptoms are usually present. Most patients do not recall a preceding tick bite. Despite a characteristic appearance, EM is not pathognomonic for Lyme disease and must be distinguished from other similar appearing skin lesions. EM is a clinical diagnosis; serologic and PCR assays are unnecessary. Leukopenia and thrombocytopenia are indicative of either an alternative diagnosis, or coinfection with another tick-borne pathogen. When EM is promptly treated with appropriate antimicrobial agents, the prognosis is excellent. Persons in endemic areas should take measures to prevent tick bites.