Human Adaptive Natural Killer Cells: Beyond NKG2C

• Autores: Julia A. Wagner, Todd A. Fehniger
• Localización: Trends in immunology, ISSN 1471-4906, Vol. 37, Nº. 6, 2016, págs. 351-353
• Idioma: inglés
• Enlaces
  • Texto completo
• Resumen

  • Paradigm-shifting studies have identified NKG2C+ adaptive natural killer (NK) cells in individuals infected with cytomegalovirus. Recently in Cell Reports, Liu et al. demonstrate that NKG2C−/− HCMV+ individuals also generate adaptive NK cells, and reveal CD2 as a major co-stimulatory receptor for these NK cells specialized to respond via FcγRIIIa/CD16.