Bacterial and fungal otitis constitutes most ear disease in companion animals. However, a wide spectrum of infectious and noninfectious disease processes involve the structures of the ear and are of primary diagnostic consideration in cases of recurrent otitis or those refractive to traditional treatments. This article discusses several common to reasonably rare neoplastic and nonneoplastic space-occupying lesions of the external, middle, and internal ear. Although some conditions present as unique entities, many present similar to or concurrent with otitis, and should be considered in cases of clinically unresponsive otitis.
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