Human Immunodeficiency Virus Vaccines

• Autores: Paul Goepfert, Anju Bansal
• Localización: Infectious disease clinics of North America, ISSN 0891-5520, Vol. 28, Nº. 4, 2014 (Ejemplar dedicado a: Updates in HIV and AIDS: Part II), págs. 615-631
• Idioma: inglés
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• Resumen

  • Although some success was achieved in recent years in HIV prevention, an effective vaccine remains the means with the most potential of curtailing HIV-1 infections worldwide. Despite multiple failed attempts, a recent HIV vaccine regimen demonstrated modest protection from infection. Although the protective efficacy in this trial was not sufficient to warrant licensure, it spurred renewed optimism in the field and has provided valuable insights for improving future vaccine designs. This review summarizes the pertinent details of vaccine development and discusses ways the field is moving forward to develop a vaccine to prevent HIV infection and disease progression.