Autoimmune Pancreatitis: An Update on Diagnosis and Management

• Autores: Kamraan Madhani, James J. Farrell
• Localización: Gastroenterology clinics of North America, ISSN 0889-8553, Vol. 45, Nº. 1, 2016 (Ejemplar dedicado a: Management of Pancreatic Diseases), págs. 29-43
• Idioma: inglés
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• Resumen

  • There is an evolving understanding that autoimmune pancreatitis (AIP) is an immunoglobulin (Ig) G4 systemic disease. It can manifest as primarily a pancreatic disorder or in association with other disorders of presumed autoimmune cause. Classic clinical characteristics include obstructive jaundice, abdominal pain, and acute pancreatitis. Thus, AIP can be difficult to distinguish from pancreatic malignancy. However, AIP may respond to therapy with corticosteroids, and has a strong association with other immune mediated diseases. Although primarily a pathologic diagnosis, attempts have been made to reliably diagnose AIP clinically. AIP can be classified as either type 1 or type 2.