Screening of antimicrobial activities in red, green and brown macroalgae from Gran Canaria (Canary Islands, Spain)

• Antonio González del Val ^[1] ; Gonzalo Platas ^[1] ; Angela Basilio ^[1] ; Angeles Cabello ^[1] ; Julian Gorrochategui ^[1] ; Inmaculada Suay ^[1] ; Francisca Vicente ^[1] ; Eduardo Portillo ^[2] ; Miguel Jiménez del Río ^[2] ; Guillermo García Reina ^[3] ; Fernando Peláez ^[1]
  1. [1] Center for Basic Research— Natural Products Drug Discovery, Merck Research Laboratories, Merck Sharp & Dohme de España, Madrid, Spain
  2. [2] Center for Applied Biological Research, Canary Islands Technological Institute, Las Palmas de Gran Canaria, Spain
  3. [3] Institute for Applied Algology, Las Palmas de Gran Canaria University, Telde, Las Palmas, Spain

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• Localización: International microbiology: official journal of the Spanish Society for Microbiology, ISSN 1139-6709, Vol. 4, Nº. 1, 2001, págs. 35-40
• Idioma: inglés
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  • Extracts from 44 species of seaweed from Gran Canaria (Canary Islands, Spain) were screened for the production of antibacterial and antifungal compounds against a panel of Gram-negative and Gram-positive bacteria, mycobacteria, yeasts and fungi. A total of 28 species displayed antibacterial activity, of which six also showed antifungal activity. Asparagopsis taxiformis and Cymopolia barbata were the species with the strongest activities against the broadest spectrum of target microorganisms. All the species with antibacterial activity were active against Gram-positive bacteria, whereas only two species, A. taxiformis and Osmundea hybrida, were active against mycobacteria. The production of secondary metabolites with antimicrobial activities by the macroalgae was also studied under different conditions, although no common trend for bioactivity was observed.