Fibrinogen replacement in trauma uncontrolled bleeding: A review of the literature

• Autores: Celia González Guerrero, José Bruno Montoro Ronsano
• Localización: European journal of clinical pharmacy: atención farmacéutica, ISSN 2385-409X, Vol. 18, Nº. 1, 2016, pág. 8
• Idioma: inglés
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• Resumen

  • There are many theoretical reasons to consider the fibrinogen replacement in the patient with Trauma-Induced Coagulopathy (TIC)􀀏 but not many conclusive highquality prospective studies have been carried out to determine its optimal efficacy and safety. The fibrinogen use is based on scarce observational data and empiric experience; while uncontrolled post-traumatic bleeding is still the leading cause of potentially preventable death among trauma patients.

    This review aims to collect the data available in PubMed about the use of fibrinogen replacement in patients with TIC