Deep Fungal Infections, Blastomycosis-Like Pyoderma, and Granulomatous Sexually Transmitted Infections

• Autores: Jacqueline A. Guidry, Christopher Downing, Stephen K. Tyring
• Localización: Dermatologic clinics, ISSN 0733-8635, Vol. 33, Nº. 3, 2015 (Ejemplar dedicado a: Granulomatous Disorders of Adult Skin), págs. 595-607
• Idioma: inglés
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• Resumen

  • Granulomatous diseases are caused by multiple infectious and noninfectious causes. Deep fungal infections can present in the skin or extracutaneously, most commonly with lung manifestations. An Azole or amphotericin B is the universal treatment. Blastomycosis-like pyoderma is a clinically similar condition, which is caused by a combination of hypersensitivity and immunosuppression. Successful treatment has been reported with antibiotics and, more recently, the vitamin A analog, acitretin. Granuloma inguinale and lymphogranuloma venereum cause ulcerative genital lesions with a granulomatous appearance on histology. The Centers for Disease Control and Prevention recommens treatment of these genital infections with doxycycline.