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Adult Xanthogranuloma, Reticulohistiocytosis, and Rosai-Dorfman Disease

  • Autores: Sarah S. Chisolm, Joshua M. Schulman, Lindy P. Fox
  • Localización: Dermatologic clinics, ISSN 0733-8635, Vol. 33, Nº. 3, 2015 (Ejemplar dedicado a: Granulomatous Disorders of Adult Skin), págs. 465-473
  • Idioma: inglés
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  • Resumen
    • Adult xanthogranuloma presents most commonly as an orange-tan firm solitary nodule with no systemic manifestations. Recently, some cases have been reported in conjunction with lymphoproliferative disorders. Adult reticulohistiocytosis classically presents as red to yellow-red dermal nodules. In the multicentric form, lesions have a predilection for hands and elbows, with a classic coral bead periungual presentation, and are often associated with symmetric erosive arthritis, particularly of the hands and wrists. The presentation and course of Rosai-Dorfman disease, or sinus histiocytosis with massive lymphadenopathy, can vary. The classic presentation is extensive, painless bilateral cervical lymphadenopathy, but some cases have been entirely extranodal.


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