How chemical information is produced, distributed, discovered, managed, shared, and preserved has changed significantly in the past two decades. The number of publications continues to grow exponentially, and most of the core chemistry literature is now available online. Understanding how to navigate this digital landscape is essential for students, educators, and researchers. Similar to calibrating and learning how to use lab instruments, developing information literacy skills enables researchers to use their time more effectively and efficiently. In response to an open call for papers, this issue contains 26 papers that are grouped into three broad subject areas: Information Skills, Prototypes and Best Practices, and Discovery. Papers in this special issue aim to be a resource for ideas and a catalyst for expanding communication and collaboration between chemists and information professionals. Because some areas of chemical information are not included in this issue, topics for future issues of the Journal of Chemical Education are suggested at the end of this editorial. Note: Papers in the Journal of Chemical Education Special Issue: Chemical Information have a designation that they are part of the collection published in this issue.
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