Averting the legacy of kidney disease. Focus on childhood.

• Autores: Julie R. Ingelfinger, Kamyar Kalantar-Zadeh, F. Schaefer, Gema García García, W.G. Couser, M.C. Riella
• Localización: Archivos españoles de urología, ISSN 0004-0614, Tomo 69, Nº. 1, 2016, págs. 1-8
• Idioma: inglés
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• Resumen

  • The 11th World Kidney Day will be celebrated on March 10, 2016, around the globe. This annual event, sponsored jointly by the International Society of Nephrology (ISN) and the International Federation of Kidney Foundations (IFKF), has become a highly successful effort to inform the general public and policymakers about the importance and ramifications of kidney disease. In 2016, World Kidney Day will be dedicated to kidney disease in childhood and the antecedents of adult kidney disease, which can begin in earliest childhood.

    Children who endure acute kidney injury (AKI) from a wide variety of conditions may have long-term sequelae that can lead to chronic kidney disease (CKD) many years later (1-4). Further, CKD in childhood, much of it congenital, and complications from the many non-renal diseases that can affect the kidneys secondarily, not only lead to substantial morbidity and mortality during childhood but also result in medical issues beyond childhood. Indeed, childhood deaths from a long list of communicable diseases are inextricably linked to kidney involvement. For example, children who succumb to cholera and other diarrheal infections often die, not from the infection, but because of AKI induced by volume depletion and shock. In addition, a substantial body of data indicates that hypertension, proteinuria and CKD in adulthood have childhood antecedents from as early as in utero and perinatal life (see Table I for definitions of childhood). World Kidney Day 2016 aims to heighten general awareness that much adult renal disease is actually initiated in childhood. Understanding high risk diagnoses and events that occur in childhood have the potential to identify and intervene preemptively in those people at higher risk for CKD during their lifetimes.