Traumatic dysesthesia of the trigeminal nerve

• Autores: Dermont Canavan, Steven B. Graff-Radford, Barton M. Gratt
• Localización: Journal of Oral & Facial Pain and Headache, ISSN-e 2333-0376, ISSN 2333-0384, Vol. 8, Nº. 4, 1994, págs. 391-396
• Idioma: inglés
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• Resumen

  • Traumatic injury to the peripheral nerves often results in persistent discomfort. Substance P has been implicated as a mediator of pain, and depletion of this neurotransmitter has been shown to reduce pain. Subjects suffering from traumatic dysesthesia of the trigeminal nerve were treated with capsaicin, a substance P depleter with significant long-term effects. This form of therapy may be used individually or in combination with other pharmacologic interventions in the treatment of traumatic trigeminal dysesthesia.