Ertapenem desensitization protocol in patient allergic to penicillin

• Autores: Laura Barrajón Pérez, Cristina Sangrador Pelluz, Matilde Martínez García, Enrique Soler Company
• Localización: European journal of clinical pharmacy: atención farmacéutica, ISSN 2385-409X, Vol. 17, Nº. 4, 2015, págs. 10-10
• Idioma: inglés
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• Resumen

  • Introduction: Ertapenem is an antibiotic with an ability of causing cross-sensitivity reactions in patients who are allergic to other beta-lactams; some of them life-threatening. The use of a Desensitization Protocol (DP) is an adequate tool for its administration in these cases, by tolerance induction.

    Case report: Patient allergic to penicillin with an infected ulcer by two bacteria sensitive to ertapenem. A literature research was performed on ertapenem desensitization techniques, not obtaining information on this issue. It was decided to design an ertapenem DP in seven steps based on other beta-lactams desensitization.

    The desensitization was carried out successfully without emergence of allergic reactions.

    Observation: The use of this DP enabled a safe and effective therapy with the drug of choice