A Green Enantioselective Aldol Condensation for the Undergraduate Organic Laboratory

• George D. Bennett ^[1]
  1. [1] Millikin University

     Millikin University

     Township of Decatur, Estados Unidos

     
• Localización: Journal of chemical education, ISSN 0021-9584, Vol. 83, Nº 12, 2006, pág. 1871
• Idioma: inglés
• Texto completo no disponible (Saber más ...)
• Resumen

  • The proline-catalyzed aldol condensation between acetone and isobutyraldehyde proceeds in good yield and with high enantioselectivity at room temperature. This multi-week experiment illustrates a number of principles of green chemistry while also revealing some of the trade-offs. This project also affords several opportunities for open-ended investigations.