Clostridium perfringens is one of the most widespread bacteria on earth, with a ubiquitous environmental presence in soil, sewage, food and faecal-contaminated material. While C perfringens is also part of the normal intestinal flora in people and animals (McClane and others 2013) it can, under certain circumstances, cause severe intra- and extra-intestinal pathologies. In human medicine C perfringens is the most important cause of gas gangrene and a variety of gastrointestinal illnesses such as food poisoning, antibiotic-associated diarrhoea and enteritis necroticans (Uzal and others 2014)....
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