Resumen de Synthesis of meso-Diethyl-2,2'-dipyrromethane in Water. An Experiment in Green Organic Chemistry
In this laboratory activity, students are introduced to the synthesis of dipyrromethanes, which are important precursors for porphyrin and calix[4]pyrrole. The acid-catalyzed condensation of pyrrole and 3-pentanone in water uses common inexpensive reagents and solvents to produce the meso-diethyl-2,2′-dipyrromethane in one step, in an analytical grade directly from the aqueous reaction medium.
