A Practical Procedure for the Solid-Phase Synthesis of Azo Compounds in the Undergraduate Organic Laboratory

• Cailan Wang ^[1] ; Xiaoxia Wang ^[1] ; Yulu Wang ^[1] ; Xiaoyang Wang ^[1] ; Hong Wang ^[1]
  1. [1] Henan Normal University

     Henan Normal University

     China

     
• Localización: Journal of chemical education, ISSN 0021-9584, Vol. 77, Nº 7 (July), 2000, págs. 903-903
• Idioma: inglés
• Texto completo no disponible (Saber más ...)
• Resumen

  • A new solid-phase reaction method used to synthesize a new type of azo compound is described. The procedure is short, safe, and simple enough to serve as a laboratory exercise for undergraduate students in the middle weeks of a course when azo compounds or synthesis methods have been discussed in the lecture. The compounds synthesized are N-(4'-ethoxyphenyl)-2-phenyl diazenecarboxamide and phenyl-2-phenylhydrazide diazenecarboxylic acid. They can easily be obtained by oxidation of N-(4'-ethoxyphenyl)-2-phenyl hydrazinecarboxamide and 2,2'-diphenyl-carbonic dihydrazide using ferric nitrate as an oxidation reagent in a solid phase reaction .

    N-(4'-Ethoxyphenyl)-2-phenyl diazenecarboxamide can be used as dye, and phenyl-2-phenylhydrazide diazenecarboxylic acid is a reagent already widely used in analytical chemistry. The experiments are also designed to demonstrate the uses of the products. All the experimental work can be completed in a three-hour period. All processes use inexpensive equipment and materials that are readily available in most undergraduate laboratories.