Enfermedad hemolítica perinatal causada por anticuerpos anti-M y tratada con inmunoglobulinas intravenosas fetales

• Lorea Ugarte Rubio ^[1] ; Maria Cuadra Cestafe ; Iñaki Lete ; Oihane Lapuente Ocamica ; Janire Gonzalez Calviño
  1. [1] Unidad de Gestión Clínica de Ginecología y Obstetricia, Hospital Universitario, Araba, Vitoria-Gasteiz, España
• Localización: Progresos de obstetricia y ginecología: revista oficial de la Sociedad Española de Ginecología y Obstetricia, ISSN 0304-5013, Vol. 58, Nº. 7, 2015, págs. 327-329
• Idioma: español
• Títulos paralelos:
  • Hemolytic disease of the fetus due to anti-M antibodies treated with fetal intravenous immunoglobulin therapy
• Enlaces
  • Texto Completo Ejemplar
• Resumen
  • español

    Anti- M alloimmunization. Fetal hemolytic disease. Fetal erythroblastosis. Intravenous immunoglobulin.

  • English

    We present the case of a 28-year-old woman with two prior late miscarriages caused by anti-M antibodies, leading to alloimmunization of her previous pregnancies. During this pregnancy, she was successfully treated with intravenous immunoglobulins administered from the 23th to the 34th week of pregnancy. There are no randomized trials to indicate whether the antenatal use of intravenous immunoglobulin is effective in the management of fetal red blood cell alloimmunization. Several case series suggest a beneficial role in preventing severe fetal anemia