Effect of Gender on the GH-IGF-I Response to Anaerobic Exercise in Young Adults

• Autores: Alon Eliakim, Dan Nemet, Guy Most, Noa Rakover, Michal Pantanowitz, Yoav Meckel
• Localización: Journal of strength and conditioning research: the research journal of the NSCA, ISSN 1064-8011, Vol. 28, Nº. 12, 2014, págs. 3411-3415
• Idioma: inglés
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• Resumen

  • Exercise-associated effects on the growth hormone-insulin-like growth factor-I (GH-IGF-I) axis were studied, mainly after aerobic exercise. We determined the gender effect on the GH-IGF-I axis response to a standard all-out Wingate anaerobic test (WAnT) in healthy active young adult men and women (men = 12 and women = 16; age range: 24-34 years). Blood samples for GH and IGF-I, key elements of the GH-IGF-I axis, were collected before and 20, 30, 40, and 60 minutes after the beginning of exercise. In addition, we collected postexercise blood lactate levels. Postexercise lactate levels were higher among men; however, this difference did not reach statistical significance (13.8 +/- 1.3 vs. 11.1 +/- 1.0 mmol[middle dot]L-1, respectively; p = 0.1). The WAnT was associated with a significant increase in GH in both genders. However, GH peak was greater among women (10.8 +/- 1.8 vs. 5.6 +/- 1.4 ng[middle dot]ml-1, in women and men, respectively; p < 0.01). In addition, postexercise GH peak occurred significantly earlier in female (20 minutes) compared with male participants (40 minutes). Exercise was associated with a significant increase in IGF only among men (from 166.8 +/- 8.4 to 186.9 +/- 9.3; p < 0.02); however, no significant between-gender effect was found. In summary, supramaximal anaerobic exercise was associated with a greater and earlier postexercise GH peak in women compared with men. All together, the results suggest anaerobic exercise-related anabolic-type hormonal response.