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Resumen de Stereoisomer Bubbles

Melanie J. Lesko

  • Undergraduate organic chemistry students are given a simple method to determine the stereochemical relationships between several molecules with more than one chiral center. The four groups around each chiral center are assigned Cahn-Ingold-Prelog priorities, and these numbers encircled in "bubbles". Subsequent structure manipulations by the allowed Fisher projection rotations involve only these four number bubbles to make R or S assignments. A table of relationships (identical, diastereomer, or enantiomer) between all the molecules is then generated.


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