Resumen de Learning about Regiochemistry from a Hydrogen-Atom Abstraction Reaction in Water

Christopher Sears-Dundes, Yoeup Huon, Richard P. Hotz, Allan R. Pinhas

• An experiment has been developed in which the hydrogen-atom abstraction and the coupling of propionitrile, using Fenton’s reagent, are investigated. Students learn about the regiochemistry of radical formation, the stereochemistry of product formation, and the interpretation of GC–MS data, in a safe reaction that can be easily completed in one laboratory session.