A Wet-Lab Approach to Stereochemistry Using 31P NMR Spectroscopy

• Owen S. Fenton ^[1] ; Bianca R. Sculimbrene ^[1]
  1. [1] College of the Holy Cross

     College of the Holy Cross

     City of Worcester, Estados Unidos

     
• Localización: Journal of chemical education, ISSN 0021-9584, Vol. 88, Nº 5, 2011, págs. 662-664
• Idioma: inglés
• Texto completo no disponible (Saber más ...)
• Resumen

  • Understanding stereochemistry is an important and difficult task for students to master in organic chemistry. In both introductory and advanced courses, students are encouraged to explore the spatial relationships between molecules, but this exploration is often limited either to the lecture hall or the confines of the library. As such, we sought to develop an experiment-based approach that would facilitate investigation of stereochemical principles in an organic chemistry laboratory. Herein is reported a 31P NMR-based experiment that allows students to explore the different stereochemical outcomes when enantiopure or racemic alcohols are coupled to an achiral phosphorous center.