Long-Term Results of Guided Tissue Regeneration Therapy With Non-Resorbable and Bioabsorbable Barriers. II. A Case Series of Infrabony Defects
- Autores: Ti-Sun Kim, Rolf Holle, Ernest Hausmann, Peter Eickholz
- Localización: Journal of periodontology, ISSN 0022-3492, Vol. 73, Nº. 4, 2002, págs. 450-459
- Idioma: inglés
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Resumen
Background: The aim of this 5-year follow-up case series was to clinically and radiographically evaluate the long-term results after guided tissue regeneration (GTR) therapy of infrabony defects using nonresorbable and bioabsorbable barriers.
Methods: In 12 patients with advanced chronic periodontitis 12 pairs of contralateral infrabony defects were treated. Within each patient one defect received a non-resorbable (expanded polytetrafluoroethylene [ePTFE]; control: C) and the other a bioabsorbable (polyglactin 910; test: T) barrier by random assignment. At baseline and at 6 and 60 ±3 months after surgery clinical parameters and standardized radiographs were obtained. Gain of bone density within infrabony defects was assessed using subtraction radiography.
Results: Eight of 12 patients were available for the 60-month reexaminations. Six and 60 ±3 months after GTR therapy statistically significant (P <0.05) vertical attachment (CAL-V) gain was observed in both groups (C6: 2.6 ±1.4 mm; C60: 1.6 ± 1.5 mm; T6: 3.0 ±1.7 mm; T60: 3.0 ±0.7 mm). However at 60 months, 2 infrabony defects in the control group had lost all the attachment that had been gained 6 months after therapy and a clinically relevant but statistically insignificant mean CAL-V loss of 1.0 ±2.1 mm was observed from 6 to 60 months. The case series failed to show statistically significant differences between test and control regarding CAL-V gain 60 months after surgery. Also subtraction analysis failed to reveal statistically significant differences regarding density gain between both groups 6 and 60 months postsurgically (C6: 26.4 ± 54.2; C60 62.8 ±112.7; T6: 68.7 ±72.8; T60. 84.1 ±83.6).
Conclusions: CAL-V gain achieved after GTR therapy in infrabony defects using both non-resorbable and bioabsorbable barriers was quite stable after 5 years in 14 of 16 defects. J Periodontol 2002;73:450-459.
