Resumen de Effects of Nd:YAG and CO2 Laser Treatment and Ultrasonic Scaling on Periodontal Pockets of Chronic Periodontitis Patients
Akira Miyazaki, Toshikazu Yamaguchi, Jun Nishikata, Kazuhiro Okuda, Satoru Suda, Kazuko Orima, Tetsuo Kobayashi, Kazuhisa Yamazaki, Eiji Yoshikawa, Dr. Hiromasa Yoshie
Background: The aim of the present study was to compare the effectiveness of Nd:YAG and CO2 laser treatment to that of ultrasonic scaling used as monotherapies by examining clinical parameters, subgingival microflora, and interleukin-1 beta (IL-1β) in gingival crevicular fluid (GCF).
Methods: Eighteen patients, each of whom had 2 or more sites with probing depth measuring >5 mm, were included this clinical trial. The 41 sites were randomly assigned treatment with either Nd:YAG laser alone (n = 14, 100 mj, 20 pps, 2.0 W, 120 seconds), CO2 laser alone (n = 13, 2.0 W, 120 seconds), or ultrasonic scaling alone (n = 14, maximum power, 120 seconds). At baseline and at 1, 4, and 12 weeks, clinical measurements (plaque index, PI; gingival index, GI; probing depth, PD; clinical attachment level, CAL; and bleeding on probing, BOP) were performed and subgingival plaque and GCF sampled. A quantitative analysis of Porphyromonas gingivalis was carried out using real-time polymerase chain reaction (PCR) procedures. The amounts of IL-1β were estimated by an enzyme-linked immunosorbent assay (ELISA).
Results: Decreased inflammation and PD were observed in all 3 groups after treatment. A microbiological analysis indicated significant decreases in P. gingivalis in the Nd:YAG and scaling groups at 1, 4, and 12 weeks compared to baseline (P <0.05). The amount of GCF significantly decreased in the Nd:YAG and scaling groups at 12 weeks. The amount of IL-1β increased in the CO2 group from baseline to 1 week (P <0.05). The Nd:YAG group tended to show a decrease in IL-1β from 1 to 12 weeks, although these data were not statistically significant.
Conclusions: Our data suggest that Nd:YAG laser and ultrasonic scaling treatments showed significant improvements regarding the clinical parameters and subgingival microflora compared to the baseline, but no significant difference was observed between the 3 groups. J Periodontol 2003;74:175-180.
