Resumen de Periodontal Status in Men With Hypergonadotropic Hypogonadism: Effects of Testosterone Deficiency
Işıl Saygun, Erol Bolu, Özlem Daltaban
Periodontal Status in Men With Hypergonadotropic Hypogonadism: Effects of Testosterone Deficiency Özlem Daltaban,* Işıl Saygun,† and Erol Bolu‡ *Faculty of Dentistry, Department of Periodontology, Gazi University, Ankara, Turkey.
†Department of Periodontology, Gülhane Military Medical Academy, Ankara, Turkey.
‡Department of Endocrinology, Gülhane Military Medical Academy.
Correspondence: Dr. Işıl Saygun, Department of Periodontology, Gülhane Military Medical Academy, 06018 Etlik, Ankara, Turkey. Fax: 90-312-3046020; e-mail: daltabanozlem@yahoo.com.
Background: The purpose of this clinical study was to evaluate the possible influence of testosterone hormone on common clinical measurements of periodontal disease in men with hypergonadotropic hypogonadism.
Methods: Twenty-four hypergonadotropic hypogonadal men (H) and 24 systemically healthy men (S) were divided into two groups as chronic periodontitis and clinically healthy controls after clinical examinations and radiographs. The H group consisted of 12 control (H/C) and 12 chronic periodontitis (H/P) patients, and the S group consisted of 12 control (S/C) and 12 chronic periodontitis (S/P) patients. Plaque index (PI), gingival index (GI), bleeding on probing (BOP), probing depth (PD), and clinical attachment loss (CAL) scores were recorded.
Results: The mean of all clinical parameters (PI, GI, BOP, PD, and CAL) were significantly (P <0.05) higher in periodontitis groups (H/P and S/P) than controls (H/C and S/C). There were no significant differences in the PD and CAL scores between periodontitis groups (S/P and H/P). The mean of GI and BOP scores were statistically higher in the H/P group than the S/P group (P <0.05). There was a negative correlation between GI and free testosterone levels (r= −0.794; P <0.05).
Conclusion: According to these results, serum testosterone levels may possibly influence periodontal disease in men, and testosterone may have an inhibitory effect on gingival inflammation.
