Resumen de Periodontal Debridement With Povidone-Iodine in Periodontal Treatment: Short-Term Clinical and Biochemical Observations

Guilherme M. Zanatta, Sandro Bittencourt, Francisco Humberto Nociti, Enilson Antonio Sallum, Antonio Wilson Sallum, Marcio Zaffalon Casati

• Background: The aim of the present study was to evaluate the clinical effects of one-stage periodontal debridement with an ultrasonic instrument, associated with 0.5% povidone (pvp)-iodine irrigation in patients with chronic periodontitis.

  Methods: Forty-five patients were randomly assigned into three groups: the control group (CG) received quadrant root planing at 1-week intervals over four consecutive sessions; the periodontal debridement plus pvp-iodine group (PD-PIG) received a 45-minute full-mouth debridement with an ultrasonic instrument, associated with 0.5% pvp-iodine irrigation; and the periodontal debridement group (PDG) received a 45-minute full-mouth periodontal debridement with an ultrasonic instrument, associated with NaCl irrigation.

  Results: At the 3-month evaluation, the mean probing depth (PD) reduction in CG was 2.51 ± 0.52 mm, 2.53 ± 0.50 mm in PD-PIG, and 2.58 ± 0.60 mm in PDG (P <0.05). The clinical attachment level (CAL) analysis showed a statistically significant gain in all groups compared to baseline (1.87 ± 0.56 mm [CG], 1.94 ± 0.70 mm [PD-PIG], and 1.99 ± 0.92 mm [PDG]). Intergroup analysis of PD and CAL at 1 and 3 months showed no differences (P >0.05). The N-benzoyl-L-arginine-p-nitroanilide (BAPNA) test showed a significant reduction in trypsin activity only during the first month (P <0.05); at 3 months there were no differences compared to baseline (P = 0.80).

  Conclusion: This study provides no evidence that pvp-iodine is effective as an adjunct for one-stage periodontal debridement.