Stability of Clinical and Radiographic Results After Guided Tissue Regeneration in Infrabony Defects

• Autores: Peter Eickholz
• Localización: Journal of periodontology, ISSN 0022-3492, Vol. 78, Nº. 1, 2007, págs. 37-46
• Idioma: inglés
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• Resumen

  • Background: The aim of this 5-year follow-up study was to evaluate clinically and radiographically the long-term results after guided tissue regeneration (GTR) therapy of infrabony defects using non-resorbable and bioabsorbable barriers.

    Methods: Thirty-one patients with periodontitis and 50 infrabony defects that had been treated using GTR were recruited. Eleven defects were treated with non-resorbable expanded polytetrafluoroethylene membranes and 39 defects with bioabsorbable barriers. At baseline and 6 and 60 ± 3 months after surgery, clinical parameters and standardized radiographs were obtained. During surgery and 60 ± 3 months thereafter, the distance from the cemento-enamel junction to the base of the bony defect (vertical probing bone level [PBL-V]) was measured. Bone gain was evaluated using digital subtraction radiography.

    Results: At 6 and 60 ± 3 months after GTR, there was a statistically significant (P <0.001) reduction of probing depth (6 months: 4.31 ± 1.76 mm; 60 months: 3.95 ± 1.62 mm) and vertical clinical attachment level gains (CAL-V) (6 months: 3.34 ± 1.66 mm; 60 months: 2.97 ± 1.53 mm). From 6 to 60 months after GTR, three infrabony defects exhibited CAL-V loss >2 mm, and a small, statistically not significant mean CAL-V loss of 0.39 ± 1.60 mm was observed. From baseline to 60 ± 3 months, a significant PBL-V gain of 1.78 ± 2.67 mm (P <0.001) and increase in bone density were observed (P = 0.003).

    Conclusion: The CAL-V gain achieved after GTR in infrabony defects using both non-resorbable and bioabsorbable barriers was stable after 5 years in 47 of 50 defects.