Effectiveness and tolerance of 0.02% chlorhexidine eye drops with an acanthamoeba keratitis

• Autores: Angela María Rizo Cerdá, Alberto Espuny Miro, G. Lucas Elio, Pablo Selvi Sabater
• Localización: European journal of clinical pharmacy: atención farmacéutica, ISSN 2385-409X, Vol. 16, Nº. 5, 2014, págs. 13-13
• Idioma: inglés
• Texto completo no disponible (Saber más ...)
• Resumen

  • Background: Evaluation of the effectiveness and safety of using chlorhexidine 0.02% eye drops developed as a magistral formula in the treatment of Acanthamoeba keratitis.

    Method: The medical record of the infected patient was reviewed and the following data were collected: symptoms and signs at the time of diagnosis, treatment instituted, adverse reactions, and both objective and subjective evolution during the process.

    Results: The patient was treated from diagnosis with propamidine isethionate (Brolene®) eye drops and chlorhexidine 0.02%. She suffered two reactivation of infection during combination therapy and finally Brolene® was suspended by corneal toxicity, remaining with topical chlorhexidine 0.02% as monotherapy to date.

    Discussion: Monotherapy with topical 0.02% chlorhexidine was effective (there was no worsening or reactivation of infection) and well tolerated. In our experience 0.02%, chlorhexidine eye drops have proven to be safe and better tolerated than Brolene®